Details for gene set INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos
Phenotype	phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos
Upregulated in class	transDMproB
GeneSet	INOH_JAK-STAT PATHWAY AND REGULATION PATHWAY
Enrichment Score (ES)	0.6250292
Normalized Enrichment Score (NES)	1.5435429
Nominal p-value	0.0
FDR q-value	0.17250475
FWER p-Value	0.826

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PSMB2	2324 16078	12	5.048	0.0622	Yes
2	KIT	16823	40	3.755	0.1076	Yes
3	GFRA1	9015	56	3.423	0.1494	Yes
4	STAT4	14251 9907	80	2.977	0.1852	Yes
5	MAPK9	1233 20903 1383	89	2.817	0.2199	Yes
6	IL12A	4913	129	2.506	0.2490	Yes
7	MAPKAPK2	13838	165	2.313	0.2759	Yes
8	MAP4K2	6457	210	2.155	0.3004	Yes
9	SOCS2	5694	217	2.127	0.3266	Yes
10	JAK3	9198 4936	320	1.798	0.3434	Yes
11	STAT3	5525 9906	396	1.605	0.3593	Yes
12	IL10	14145 1510 1553 22902	408	1.592	0.3786	Yes
13	CAMK2B	20536	457	1.521	0.3949	Yes
14	MAP3K3	20626	496	1.448	0.4109	Yes
15	PSMB9	23021	520	1.412	0.4272	Yes
16	LCK	15746	521	1.410	0.4448	Yes
17	STAT1	3936 5524	531	1.404	0.4618	Yes
18	PSMA3	9632 5298	613	1.250	0.4730	Yes
19	MAP3K14	11998	645	1.197	0.4862	Yes
20	MAP3K11	11163	734	1.072	0.4948	Yes
21	MAPK14	23313	872	0.931	0.4990	Yes
22	PDPK1	23097	914	0.896	0.5079	Yes
23	PRKCH	21246	1030	0.813	0.5118	Yes
24	PRKCD	21897	1031	0.813	0.5219	Yes
25	BTK	24061	1069	0.787	0.5297	Yes
26	MAP3K5	20079 11166	1088	0.768	0.5383	Yes
27	PAK4	17909	1147	0.717	0.5441	Yes
28	MAP4K3	22887	1158	0.707	0.5524	Yes
29	RIPK1	5381	1189	0.687	0.5593	Yes
30	STAT5A	20664	1207	0.676	0.5668	Yes
31	MAP3K1	21348	1290	0.626	0.5701	Yes
32	MKNK2	3299 9392	1390	0.578	0.5720	Yes
33	TNFSF10	15626	1405	0.570	0.5783	Yes
34	JAK1	15827	1468	0.543	0.5817	Yes
35	TEC	16514	1558	0.496	0.5831	Yes
36	PSMB8	5000	1587	0.486	0.5876	Yes
37	STAT2	19840	1624	0.469	0.5915	Yes
38	KRAS	9247	1683	0.444	0.5939	Yes
39	CAMK2G	21905	1726	0.420	0.5968	Yes
40	SOCS3	20131	1763	0.406	0.5999	Yes
41	GSK3B	22761	1874	0.364	0.5985	Yes
42	SOS2	21049	1883	0.362	0.6026	Yes
43	AKT3	13739 982	1896	0.357	0.6064	Yes
44	PTK2B	21776	1904	0.355	0.6104	Yes
45	GRB2	20149	1927	0.347	0.6136	Yes
46	IL1B	14431	1961	0.336	0.6160	Yes
47	MAP2K3	20856	1975	0.333	0.6194	Yes
48	ACVR1	4334	1996	0.324	0.6224	Yes
49	TYK2	12058 19215	2046	0.310	0.6236	Yes
50	CDK5	16591	2088	0.297	0.6250	Yes
51	CDK2	3438 3373 19592 3322	2297	0.243	0.6168	No
52	CSK	8805	2369	0.230	0.6158	No
53	CDK4	3424 19859	2370	0.230	0.6186	No
54	MAPK3	6458 11170	2440	0.214	0.6176	No
55	IKBKE	67	2498	0.200	0.6170	No
56	MAP3K8	23495	2611	0.176	0.6131	No
57	CDK6	16600	2683	0.159	0.6112	No
58	IGF1R	9157	2687	0.158	0.6130	No
59	RPS6KA1	15725	2699	0.155	0.6143	No
60	PAK1	9527	2858	0.127	0.6073	No
61	MAP3K7	16255	3003	0.105	0.6008	No
62	RAF1	17035	3038	0.101	0.6003	No
63	ACVR2B	19276	3128	0.092	0.5966	No
64	MAP2K1	19082	3174	0.087	0.5952	No
65	MAPK13	23314	3189	0.086	0.5955	No
66	PSMB10	5299 18761	3198	0.085	0.5962	No
67	FGFR2	1917 4722 1119	3240	0.081	0.5949	No
68	PDGFRB	23539	3339	0.072	0.5905	No
69	IL7	4921	3442	0.063	0.5858	No
70	LTK	14467	3451	0.063	0.5861	No
71	CSNK1E	6570 2211 11332	3467	0.062	0.5861	No
72	ARAF	24367	3602	0.052	0.5794	No
73	CAMK2A	2024 23541 1980	3717	0.046	0.5738	No
74	ALK	8574	3977	0.034	0.5602	No
75	ACVR2A	8542	4102	0.029	0.5538	No
76	FLT1	3483 16287	4212	0.026	0.5482	No
77	BMPR2	14241 4081	4228	0.026	0.5477	No
78	MAPK7	1381 20414	4301	0.024	0.5441	No
79	IL18	9172	4373	0.022	0.5405	No
80	TNF	23004	4411	0.021	0.5388	No
81	CSF2	20454	4560	0.018	0.5310	No
82	IL11	17981	4592	0.017	0.5295	No
83	ZAP70	14271 4042	4669	0.016	0.5256	No
84	SOS1	5476	4722	0.015	0.5229	No
85	KITLG	19889 3342	4811	0.014	0.5183	No
86	CSF3	1394 20671	4924	0.013	0.5124	No
87	ACVRL1	22354	5159	0.011	0.4998	No
88	EPO	8911	5254	0.010	0.4949	No
89	TGFBR1	16213 10165 5745	5364	0.009	0.4891	No
90	IFNB1	15846	5648	0.007	0.4738	No
91	PRKG1	5289	5810	0.007	0.4651	No
92	LTA	23003	5892	0.006	0.4608	No
93	MAP3K2	11165	6028	0.006	0.4536	No
94	SOCS5	1619 23141	6140	0.005	0.4476	No
95	PSMA6	21270	6339	0.004	0.4369	No
96	RIPK2	2528 15935	6498	0.004	0.4284	No
97	BMPR1B	8661 15152 4451	6558	0.004	0.4252	No
98	SOCS6	12042 7044	6792	0.003	0.4126	No
99	IL12B	20918	7262	0.002	0.3872	No
100	PSMA1	1627 17669	7335	0.002	0.3833	No
101	FASLG	13789	7673	0.001	0.3650	No
102	PRKAR2B	5288 2107	7813	0.000	0.3575	No
103	FGFR1	3789 8968	8129	-0.000	0.3404	No
104	PRKCI	9576	8313	-0.001	0.3304	No
105	RPS6KA2	9759 9758	8473	-0.001	0.3218	No
106	PAK3	9528	8538	-0.001	0.3184	No
107	ITK	4934	8570	-0.001	0.3167	No
108	STAT5B	20222	8729	-0.002	0.3081	No
109	IL17A	14289	8833	-0.002	0.3026	No
110	NGFR	5174	9182	-0.003	0.2837	No
111	CD40LG	24330	9253	-0.003	0.2799	No
112	THPO	22636	9280	-0.003	0.2786	No
113	MOS	16254	9303	-0.003	0.2774	No
114	IL4	9174	9384	-0.003	0.2731	No
115	FYN	3375 3395 20052	9586	-0.004	0.2623	No
116	MAPKAPK5	16387	9650	-0.004	0.2589	No
117	PTPN11	5326 16391 9660	9713	-0.004	0.2556	No
118	PRKCE	9575	10001	-0.005	0.2401	No
119	KDR	16509	10086	-0.005	0.2356	No
120	AKT2	4365 4366	10087	-0.005	0.2356	No
121	PRKCQ	2873 2831	10097	-0.005	0.2352	No
122	IL2	15354	10226	-0.006	0.2283	No
123	IL9	21444	10313	-0.006	0.2237	No
124	IKBKG	2570 2562 4908	10346	-0.006	0.2221	No
125	IL6	16895	10903	-0.008	0.1920	No
126	PLK1	9590 5266	10979	-0.008	0.1880	No
127	IL3	20453	11254	-0.009	0.1732	No
128	SRC	5507	11341	-0.009	0.1687	No
129	BMPR1A	8660 4450	11430	-0.010	0.1640	No
130	CDK7	21365	11644	-0.011	0.1526	No
131	PRKCA	20174	11674	-0.011	0.1512	No
132	PRKAR1B	16320	11799	-0.012	0.1446	No
133	JAK2	23893 9197 3706	11807	-0.012	0.1443	No
134	PDGFRA	16824	11924	-0.012	0.1382	No
135	PRKACA	18549 3844	11943	-0.012	0.1374	No
136	FGFR3	8969 3566	12054	-0.013	0.1316	No
137	IL1A	4915	12109	-0.013	0.1288	No
138	MET	17520	12124	-0.013	0.1282	No
139	IFNG	19869	12480	-0.016	0.1091	No
140	EGFR	1329 20944	12610	-0.017	0.1024	No
141	FGFR4	3226	12709	-0.018	0.0973	No
142	TGFBR2	2994 3001 10167	13012	-0.021	0.0811	No
143	RPS6KB2	7198	13037	-0.021	0.0801	No
144	SOCS7	5308 20679	13105	-0.022	0.0767	No
145	FLT4	20904 1461	13136	-0.022	0.0754	No
146	AKT1	8568	13176	-0.023	0.0735	No
147	IL5	20884 10220	13198	-0.023	0.0727	No
148	IL15	18826 3801	13472	-0.027	0.0582	No
149	MAPK10	11169	13498	-0.027	0.0572	No
150	WEE1	18127	13773	-0.032	0.0427	No
151	INSR	18950	13984	-0.036	0.0318	No
152	MAPK11	2264 9618 22163	14100	-0.039	0.0260	No
153	PSMA2	9631	14521	-0.051	0.0038	No
154	LIF	956 667 20960	14523	-0.051	0.0044	No
155	NLK	5179 5178	14530	-0.051	0.0047	No
156	PRKG2	74	14843	-0.066	-0.0114	No
157	RPS6KA3	8490	14937	-0.071	-0.0155	No
158	MAP3K12	6454 11164	15194	-0.089	-0.0283	No
159	PRKCZ	5260	15276	-0.095	-0.0315	No
160	MAP2K6	20614 1414	15369	-0.106	-0.0352	No
161	IL13	20461	15391	-0.109	-0.0350	No
162	SYK	21636	15422	-0.112	-0.0352	No
163	PSMB6	9634	15513	-0.122	-0.0386	No
164	IRAK4	22379 11185	15529	-0.124	-0.0379	No
165	PSMB4	15252	15604	-0.133	-0.0402	No
166	MAP2K4	20405	15611	-0.134	-0.0389	No
167	MKNK1	2504	15624	-0.136	-0.0378	No
168	GRK6	6449	15684	-0.144	-0.0392	No
169	MAP2K2	19933	15726	-0.151	-0.0396	No
170	MNAT1	9396 2161	15837	-0.169	-0.0434	No
171	PSMA5	6464	16033	-0.205	-0.0515	No
172	PAK2	10310 5875	16141	-0.223	-0.0545	No
173	NRAS	5191	16222	-0.243	-0.0558	No
174	MAPK8	6459	16226	-0.245	-0.0529	No
175	IRAK1	4916	16274	-0.256	-0.0523	No
176	IKBKB	4907	16287	-0.259	-0.0497	No
177	PLK3	15790	16505	-0.311	-0.0576	No
178	RIPK3	21817	16528	-0.316	-0.0549	No
179	PSMA4	11179	16542	-0.322	-0.0516	No
180	HRAS	4868	16569	-0.329	-0.0489	No
181	SOCS4	7424	16587	-0.334	-0.0456	No
182	SOCS1	4522	16690	-0.364	-0.0466	No
183	PSMB1	23118	16692	-0.364	-0.0422	No
184	CCNH	7322	17056	-0.491	-0.0558	No
185	PSMB3	11180	17142	-0.525	-0.0538	No
186	MAPK12	2182 2215 22164	17159	-0.534	-0.0481	No
187	CHUK	23665	17214	-0.556	-0.0441	No
188	PTPN6	17002	17395	-0.639	-0.0459	No
189	PSMB7	2795 14598	17431	-0.662	-0.0395	No
190	PSMA7	14318	17465	-0.679	-0.0329	No
191	PRKAR2A	5287	17536	-0.722	-0.0277	No
192	PSMC1	9635	17562	-0.741	-0.0198	No
193	RYK	19338 3870	17617	-0.772	-0.0131	No
194	PSMB5	9633	17652	-0.804	-0.0049	No
195	PSMD2	10137 5724	18443	-2.041	-0.0224	No
196	PTK2	22271	18532	-2.547	0.0046	No